The Molecular Basis of Human Cancer

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INFORMATION
DATE DE PUBLICATION 2016-Nov-13
AUTEUR William B. Coleman
ISBN 9781934115183
TAILLE DU FICHIER 4,40 MB
TÉLÉCHARGER
LIRE EN LIGNE
DESCRIPTION
This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteom-ics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care.
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This has previously been reviewed on the molecular biology of human oral cancer. ... Among these, HPV holds a prominent position, there are more than 77 types have been identified and categorized on the basis of differences in DNA sequences. HPV types 2, 6, 11, 16, 18, 31, 33, 35 have been detected in oral epithelial dysplasia. Approximately 33-50% of OSCCs are infected with HPV-16 and 18 ...

Molecular biology holds great promise for the development of new strategies for cancer prevention and treatment. In The Molecular Basis of Human Cancer, internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing ...

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